Principal Database Developer

Our commitment to developing our staff is only surpassed by our commitment to advancing treatment options available to patients. At Cytel, we work hard to create successful careers with significant professional growth for our employees and as a result work hard to make Cytel successful. Cytel is a place where talent, experience, and integrity come together to advance the state of clinical development.

Who Are You?

We are seeking a highly experienced and strategic Principal Database Developer to lead the transformation of clinical data infrastructure. This role is pivotal in reengineering core database development workflows, designing scalable and compliant data systems, and ensuring seamless integration across clinical trial phases. You are passionate about innovation, thrive in collaborative environments, and consistently push the boundaries of what clinical data systems can achieve.

Sponsor-dedicated:

Working fully embedded within one of our pharmaceutical clients, with the support of Cytel right behind you, you'll be at the heart of our client's innovation. As a Principal Database Developer you will be dedicated to one of our global pharmaceutical clients; a company that is driving the next generation of patient treatment, where individuals are empowered to work with autonomy and ownership. You will be part of the team focused on this transformation initiative with support from both Cytel and our Client. This is an exciting time to be a part of this new program.

As a Principal Database Developer, your responsibilities will include:

Process Reengineering & Oversight:

Collaborate on the redesign of database development workflows to enhance efficiency, quality, and cross-functional integration.

Evaluate and revise existing procedures to align with evolving technologies and internal capabilities.

SOP & Process Flow Development:

Develop and maintain SOPs and technical documentation that outline database lifecycle processes and standards.

Create interactive process maps to support cross-functional understanding and training.

Functional Area Ownership:

Contribute to processes critical to database development functions including but not limited to:

EDC Design and Configuration

Integration of External Data Sources

Clinical Coding

SAE Reconciliation

Data Validation and Quality Control

Blinding and Unblinding Procedures

Database Lock and Archival Processes

Cross-Functional Collaboration:

Partner with Data Management leaders and cross-functional workstream groups to ensure database solutions meet requirements and ensure alignment with broader program goals.

Provide subject matter expertise and strategic input to support project planning and execution.

Quality & Compliance:

Ensure all database systems and deliverables meet regulatory requirements and internal quality standards.

Support audit readiness and continuous improvement initiatives.

Following project completion may transition into a hands-on Clinical Database Developer Role, where responsibilities may include but not be limited to:

CRF Development

Edit check creation

Study setup

Integration of external data sources with EDC

UAT of EDC

RAVE support during study

Data standards governance

Maintaining audit readiness

Here at Cytel we want our employees to succeed and we enable this success through consistent training, development and support. To be successful in this position you will have:

Bachelor's degree in Life Sciences, Health Informatics, or related field

10+ years of progressive experience in clinical database programming, with significant experience in a leadership or principal-level role.

Proven expertise in process development, SOP writing, and cross-functional collaboration.

Strong knowledge of database architecture, EDC systems (Medidata Rave), and clinical data standards.

Excellent communication, organizational, and problem-solving skills.

An equivalent combination of education and experience may be considered in lieu of stated requirements.

Cytel is a Global CRO providing ground-breaking biostatistical software and services to large pharma and emerging Biotech clients globally. With our patients at the centre of all that we do, we help to accelerate the development of drugs and devices that save lives and improve quality of life.

At Cytel, our focus is to provide you with a comprehensive and competitive total reward package. In addition, our world class employee benefits, supportive policies and wellbeing initiatives are tailored to support you and your family at all stages of your career - both now, and into the future.

Cytel Inc. is an Equal Employment / Affirmative Action Employer. Applicants are considered for all positions without regard to race, color, religion, sex, national origin, age, veteran status, disability, sexual orientation, gender identity or expression, or any other characteristics protected by law.